Transdermal cBHRT use is associated with a significantly lower incidence of increased mammographic breast density and breast tenderness compared with oral HRT.
Hormone replacement therapy and breast density changes Climacteric. 2005 Jun;8(2):185-92. J Harvey1, C Scheurer2, FT Kawakami2, E Quebe-Fehling2, P Ibarra de Palacios2 and VV Ragavan. University of Virginia, USA. Objectives To compare the incidence of increased breast density and tenderness in postmenopausal women associated with transdermal (Estalis/Combipatch®, Novartis, Basel, Switzerland) and oral (Kliogest®, Schering AG, …